DIABETES results when the body makes too little insulin or does not use insulin properly, allowing sugar levels to build up in the blood stream. The free radicals are one of the important etiological factors for the development of diabetes and its complications. Antioxidants capable of protecting against the damage induced by free radicals & it also have a role in reducing the effects of diabetes.
There are many herbal medicinal plants like Babul, Bilva , Davana, Neeam, Jambu etc with proven antidiabetic & related beneficial effects.
Aim - To study the effect Bilvapatra (Leaves extract of aegle marmelos) in type 2 DM
MATERIALS AND METHODS
TYPE OF STUDY: Open randomized uncontrolled clinical trial
No. of patients : 30.
Study centre: OPD of the institute.
Drug: Bilvapatra leaves extract.
Duration of treatment- 12 weeks.
Patients having signs and symptoms of type 2 Diabetes mellitus.
Pts having fasting BSL between 126-220 & post prandial between 200-400 were taken for the study. Patients were examine before & after clinically & pathologically.
Investigations: Haemogram, BSL fasting & PP, LFT, RFT,Lipid profile ,HbA1c and Urine –R & M were done before & after.
OBSERVATIONS AND RESULTS
Mean BSL fasting B.T was 154.6 with sd 22.10.while Mean BSL fasting A.T.was 132.6 with sd of 23.53 with mean diff.of 22.56 & sd 4.225.
MEAN BSL PP B.T.Was 234.4 sd 35.804 while Mean BSL post prandial A.T. was 205.5 with Sd 38.62.
Mean HbA1c B.T. was 8.08 with Sd 1.052 while Mean HbA1c A.T. was 7.45 with Sd 0.902 .
Mean Urine Sugar B.T. was 1.53 with Sd 0.8193 while Mean Urine sugar A.T. was 0.56 with Sd 0.6261.
All above parameters were statistically found significant with paired “t”-test.The average symptomatic relief was 64.40 %.
Bilvapatra can be used as an Adjuvant therapy in type 2 DM.